Vical shares sink after drug fails in testing

SAN DIEGO (AP) -- Shares of Vical Inc. plunged 51 percent Monday after the drug developer said its potential cancer treatment failed in a late-stage study, and that it would now shift its focus to infectious disease vaccines.

Allovectin did not show a statistically significant improvement in either response rate or overall survival when compared with chemotherapy in patients with metastatic melanoma, which is an advanced form of the deadliest type of skin cancer.

Vical has several independent and collaborative infectious disease vaccine programs. The San Diego company is planning to start an early-stage study of a vaccine against herpes simplex virus type 2 before the end of the year.

Vical said it had $70 million in cash and investments as of June 30, which it believes will meet its needs at least through the end of 2014.

"In the coming weeks, we will make the necessary changes to focus resources on our infectious disease vaccine programs and reduce expenses to conserve cash," CEO Vijay B. Samant said in a statement from the company.

Vical's shares $1.83 to hit $1.75 before the opening bell. The shares had climbed 23 percent so far in 2013 as of Friday's closing price of $3.58.

Source: http://news.yahoo.com/vical-shares-sink-drug-fails-112600763.html

K Michelle Lady Gaga Kendrick Lamar Hunter Hayes Dufnering Whitey Bulger Jason Dufner

Israel names Palestinians to be freed before peace talks

By Jeffrey Heller

JERUSALEM | Mon Aug 12, 2013 3:12pm EDT

JERUSALEM (Reuters) - Israel named 26 Palestinians on Monday it will free from jail this week under a deal enabling U.S.-backed peace talks to resume.

But the goodwill gesture was clouded by new plans to expand Israeli settlements that the United Nations and European Union condemned as illegal and which the Palestinians said were aimed at provoking them to pull out of the negotiations.

The 26 prisoners are the first of a total of 104 that Israel has decided in principle to free as part of an agreement reached after shuttle diplomacy by U.S. Secretary of State John Kerry to renew talks for Palestinian statehood.

Some Israelis reacted angrily to the release - scheduled for Tuesday or Wednesday - of the long-term Palestinian prisoners.

"Shame on the government and shame on the prime minister and his supporters," Zvia Dahan, whose father, Moshe Becker, was killed while tending his orange grove in Israel in 1994, wrote on Facebook. One of Becker's three killers is to be freed.

Israel sweetened the deal for far-right members of its governing coalition on Sunday by announcing plans to build 1,187 new dwellings for Jewish settlers in the occupied West Bank and parts of the territory it annexed to Jerusalem after the 1967 Middle East war.

Israel's Channel 10 television said another 900 units were planned for the Beit Jallah area near Bethlehem. An official in Prime Minister Benjamin Netanyahu's office said in response that the project was not yet under construction.

"Those who do these things are determined to undermine the peace negotiations, are determined to force people like us to leave the negotiating table," Palestinian chief negotiator Saeb Erekat told Reuters.

A spokesman for European Union foreign policy chief Catherine Ashton said: "Israeli settlements in the West Bank are illegal under international law and threaten to make a two-state solution to the Israeli-Palestinian conflict impossible."

Eduardo del Buey, spokesman for U.N. Secretary-General Ban Ki-moon, said: "settlements in the occupied territories are illegal, they have been and continue to be illegal".

Mark Regev, a spokesman for Netanyahu, said the new construction would take place in areas that Israel intends to keep in any peace agreement. "This in no way changes the final map of peace. It changes nothing," he said.

Some 500,000 Israeli settlers live in the West Bank and East Jerusalem amid 2.5 million Palestinians. Israel withdrew in 2005 from the Gaza Strip, which is now governed by Hamas Islamists opposed to permanent co-existence with the Jewish state.

LOW EXPECTATIONS

Peace talks halted three years ago in a row over settlement building. They resumed in Washington on July 30, with a second round due in Jerusalem on Wednesday and later in the West Bank.

Few expect the latest negotiations to resolve issues that have defied solution for decades, such as borders, settlements, Jerusalem and Palestinian refugees.

Washington, which pressed Palestinian President Mahmoud Abbas to return to the table, wants a deal within nine months.

With neighboring Egypt and Syria in upheaval and with Israel facing the threat of a potentially nuclear-armed Iran, Netanyahu decided he could ill afford to alienate the United States, and led his pro-settlement government into the talks.

The decision to free the 26 prisoners, regarded as heroes by Palestinians and jailed as murderers by Israel between 1985 and 1994, was made late on Sunday.

A list of the prisoners, along with the names of the people they were convicted of killing, was published by Israel's Prisons Service as part of a process in which opponents of their release have 48 hours to appeal to the High Court. Based on past decisions, the court is widely expected not to intervene.

"I cannot believe (it), no matter what anyone tells me, until I hold my son's hand. When I touch him, then I can say my son has come home," said Emtawe el Khor, whose son Fayez has been in jail since 1985, convicted of murdering an Israeli.

Fourteen of those going free will be deported or sent to the Gaza Strip, and 12 to the West Bank. Two would have completed their terms in six months, and six over the next three years.

Israel has a number of times freed Palestinians before they served out their time, but mostly in swaps for Israeli soldiers or their remains held by its enemies.

For Abbas, who has vowed to seek freedom for all Palestinian prisoners, the prospective release is a boost after years of failed talks with Israel. Many of the inmates were said to have been linked to his Fatah movement or one of its allies.

(Additional reporting by Allyn Fisher-Ilan and Ori Lewis; Editing by Alistair Lyon and Robin Pomeroy)

Source: http://www.reuters.com/article/2013/08/12/us-palestinians-israel-idUSBRE97A06320130812?feedType=RSS&feedName=worldNews

office max office max jcp Sports Authority Hollister old navy walmart black friday

RIM has announced that BBM will be available for iPhone and Android users by the...

Sorry, Readability was unable to parse this page for content.

Source: http://www.facebook.com/photo.php?fbid=10151783985947431&set=a.10150104764632431.290978.173833772430&type=1

Susan Rice the Who jon bon jovi jon bon jovi Kliff Kingsbury Amish Mafia Dave Grohl

New Zealand Rugby Union attempt to lure Sonny Bill Williams back to All Blacks

By Nik Simon

PUBLISHED: 07:33 EST, 11 August 2013 | UPDATED: 07:35 EST, 11 August 2013

The New Zealand Rugby Union are hoping to lure Sonny Bill Williams back to the All Blacks in time for the 2015 Rugby World Cup.

Reports in New Zealand suggest the 28-year-old has been offered a three-year contract that would see him switch codes from rugby league to rugby union before next year's Super Rugby championships.

Williams is one of the most gifted New Zealanders of his generation but his All Blacks career has been balanced with a talent for rugby league and boxing.

Talent: Williams takes on the England defence in the 2010 Autumn Internationals

Code switcher: Williams in action for rugby league's Sydney Roosters in July

The centre is currently playing for the Sydney Roosters in Australia's National Rugby League and if the NZRU succeed in their bid it would be the fourth time Williams has switched codes.

'We have made Sonny and Khoder [Williams' manager] an offer,' said NZRU CEO Steve Tew.

'We have been talking to them and the dialogue has been positive but we don't have any ink on paper.

'We would obviously love Sonny to come back and play rugby here and we have made that clear - it is up to Sonny and Khoder now.'

If the deal goes ahead then Williams will have the opportunity to add to his 19 All Black caps at the forthcoming World Cup in England and Wales.

While there will be no shortage of foreign interest in the player's services, Williams has already indicated that he would like a return to the Hamilton-based Chiefs.

Big hitter: Williams poses with boxing trainers Tony Mundine and Anthony Mindine

Power: Williams takes on two Irish defenders at New Zealand's Waikato Stadium

?

Share or comment on this article

MOST WATCHED SPORT VIDEOS

Source: http://www.dailymail.co.uk/sport/rugbyunion/article-2389170/New-Zealand-Rugby-Union-attempt-lure-Sonny-Bill-Williams-All-Blacks.html?ITO=1490&ns_mchannel=rss&ns_campaign=1490

wfaa prince david beckham Bill Hader tim mcgraw WWE Extreme Rules 2013 powerball winner

Braves' 14-game win streak ends, fall 1-0 to Miami

Miami Marlins starting pitcher Nate Eovaldi (24) works in the first inning of a baseball game against the Atlanta Braves in Atlanta, Saturday, Aug. 10, 2013. (AP Photo/John Bazemore)

Miami Marlins starting pitcher Nate Eovaldi (24) works in the first inning of a baseball game against the Atlanta Braves in Atlanta, Saturday, Aug. 10, 2013. (AP Photo/John Bazemore)

Atlanta Braves pitcher Alex Wood works in the first inning of a baseball game against the Miami Marlins in Atlanta, Saturday, Aug. 10, 2013. (AP Photo/John Bazemore)

Atlanta Braves right fielder Jason Heyward makes a diving catch to retire Miami Marlins' Adeiny Hechavarria in the first inning of a baseball game in Atlanta, Saturday, Aug. 10, 2013. (AP Photo/John Bazemore)

Miami Marlins Adeiny Hechavarria (3) is greeted at the dugout after scoring the go-ahead run on a wild pitch in the eighth inning of a baseball game against the Atlanta Braves in Atlanta, Saturday, Aug. 10, 2013. Miami won 1-0. (AP Photo/John Bazemore)

Miami Marlins starting pitcher Nate Eovaldi works in the first inning of a baseball game against the Atlanta Braves in Atlanta, Saturday, Aug. 10, 2013. (AP Photo/John Bazemore)

ATLANTA (AP) ? Evan Gattis blames himself for not getting his catcher's mitt lower and keeping Adeiny Hechavarria from scoring on a wild pitch.

Had he done so, the Atlanta Braves might still have a long winning streak, but Gattis says the team's goal now is to win the three-game series.

"Yeah, man, we had a good run," Gattis said. "I hate that it ended."

The Braves' 14-game winning streak ended Saturday night with a 1-0 loss to the last-place Miami Marlins, who scored on reliever Jordan Walden's wild pitch in the ninth inning.

Miami stopped its own six-game skid.

The Braves fell one victory shy of tying the 2000 team for the franchise's longest winning streak since the 1891 Boston Beaneaters won 18 straight.

Hechavarria led off the Miami ninth with a triple and scored on the wild pitch by Walden (4-2).

"I'm more disappointed in not blocking it," Gattis said. "I didn't see the replay, but I'm pretty sure I just came up on it. I think it went through me. I just came up on it a little bit with my mitt."

Marlins starter Nate Eovaldi allowed one hit in seven innings. Mike Dunn (3-3) got the win and Steve Cishek earned his 24th save, striking out Paul Janish with a runner on first to end it.

Both teams finished with just three hits.

Hechavarria's NL-leading sixth triple bounced against the bottom of the wall in left-center field and was the game's only extra-base hit. He scored standing up ? ending the Marlins' 22-inning scoreless string ? when Walden's fourth pitch to the next batter, Ed Lucas, got past Gattis.

Cishek posted his 19th straight save. He got Justin Upton to line out and Freddie Freeman to ground out before Gattis singled. Janish took a called third strike.

Chad Qualls recorded one out in the Atlanta eighth before Andrelton Simmons reached on an infield hit. Dunn struck out pinch-hitter Brian McCann and retired Jason Heyward on a groundout.

Eovaldi allowed a first-inning single by Freeman and retired his final 14 batters. He walked three and struck out eight.

"They're a great team," Eovaldi said. "I threw the ball really well tonight, It was just a great win all around."

Braves rookie starter Alex Wood had retired 12 straight batters before Jeff Mathis singled with two outs in the fifth. Wood gave up two hits, struck out seven and walked one in six innings.

Relievers David Carpenter and Luis Avilan combined to allow no baserunners and strike out three over the next two innings.

Eovaldi received no run support for his fifth straight start. The Marlins haven't scored while Eovaldi has been in a game since his 8-3 victory over Washington on July 12. He has a 1.04 ERA in his last four starts.

"He's always had a good arm to me," Heyward said after going 0 for 3. "Attacks the strike zone, has a lot of movement on his pitches, especially the fastball. Sometimes it's a little bit wild and effective as far as which side of the plate."

Braves third baseman Chris Johnson, who leads the NL with a .338 batting average, was ejected by plate umpire Jim Joyce to end the first after taking three pitches ? all fastballs ? for strikes with runners on first and second.

Johnson yelled at Joyce and threw his bat and helmet before walking to the dugout. After a 54-minute rain delay, Janish replaced Johnson.

Johnson was upset with himself for not being in the batter's box with two out in the ninth.

"Yeah, I'm one of those guys that wants to be in the game the whole time and wants to be in that spot," he said. "So, yeah, I'm definitely kicking myself a little bit."

Marlins outfielder Giancarlo Stanton didn't play. Manager Mike Redmond said he gave his star the night off because "it seems like he's just really grinding and not having a whole lot of fun out there."

The Marlins have the NL's worst winning percentage and they're last in the majors in homers, RBIs and slugging percentage.

NOTES: Walden left the game after taking a liner off his pitching hand from Logan Morrison, the third batter he faced. Braves manager Fredi Gonzalez said Walden might need a couple of days to rest his hand, but added that the injury didn't appear serious. ... RHP Anthony Varvaro got Atlanta's final out in the ninth. ... McCann was held out of the lineup with a sore knee as Gattis took his place. ... Atlanta OF Jordan Schafer was activated from a rehab assignment before the game and optioned OF Jose Constanza to Triple-A Gwinnett. ... Upton went 0 for 4 to end a 13-game hitting streak.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-08-10-BBN-Marlins-Braves/id-7847d77a498242df9e512dc9f080cdc0

HMS Bounty dominion power Heather Clem Con Edison LaGuardia Airport the weather channel national grid

'Percy Jackson and the Sea of Monsters': Your catch-up guide to the book series and movies

"Percy Jackson and the Sea of Monsters," the second installment in the movie adaptations of the "Percy Jackson" series, arrived in theaters Aug. 7. Are you wondering why your child suddenly knows all about Greek goddess Persephone? Or feeling mystified by the movie trailers? Here's our quick guide to all things Percy.

- Molly Driscoll,?Staff Writer

1. Riordan's universe

Rick Riordan's "Percy Jackson" series consists of five books, beginning with "Percy Jackson & The Olympians: The Lightning Thief" and ending with "Percy Jackson & The Olympians: The Last Olympian." The books are set in a universe that looks very much like our modern-day world but also includes the Greek gods as well as monsters from the Greek myths.

Riordan himself taught middle school social studies and English for several years, among other teaching experience. "I taught mythology almost every year that I was a teacher," the author writes on his website. "It was always my favorite thing, and the students always liked it, too!"

The author says he got the idea for the "Jackson" series when his son, Patrick, asked him to tell the Greek legends as bedtime stories. "When I ran out of myths, he was disappointed and asked me if I could make up something new with the same characters," Riordan said. The author created Percy Jackson and told Patrick the story of Percy's quest for the lightning bolt.

Source: http://www.csmonitor.com/Books/2013/0809/Percy-Jackson-and-the-Sea-of-Monsters-Your-catch-up-guide-to-the-book-series-and-movies

El Chapo Guzman Christmas Abbott clive davis nba trade thomas robinson nba trades Xbox 720

Man Critical After Fire At Queens Chinese Restaurant

'); if(infobox=='True' && ShowInfoBox_l187006_1==false){ jQuery("#player_infobarl187006_1").trigger('click'); ShowInfoBox_l187006_1==true; } }; if (false) { $.setup_player(Play_Conf); } //info bar setup jQuery('#player_infobarl187006_1').click(function() { var $info =jQuery('#player_info_contentl187006_1'); if($info.text()!=''){ var $content = jQuery('div',$info); //min heigth var min = $content.css('min-height'); var max = $content.css('max-height'); $info.slideToggle(600); ShowInfoBox_l187006_1=!ShowInfoBox_l187006_1; } }); });

? To view our videos, you need to
enable JavaScript. Learn how.
install Adobe Flash 9 or above. Install now.

Then come back here and refresh the page.

The owner of a Queens Chinese restaurant is in critical condition after a fire broke out Saturday night.

The fire happened at the Emperor House Chinese Restaurant on 10th Avenue near the Cross Island Parkway in Whitestone.

Authorities say the fire started in the kitchen on the first floor of the building.

"We heard, like, a bomb start exploding, some kind of exploding sounds, and our wall was a little shake," said one witness. "And later, next door, the owner of the Chinese, the Chinese guy was on fire, and then his wife and child were burnt. That's what happened."

Three firefighters and another person were treated for minor injuries.

Source: http://www.ny1.com/content/top_stories/187006/man-critical-after-fire-at-queens-chinese-restaurant

lunar eclipse Sunil Tripathi Tavon Austin Ella Fitzgerald Kenny Vaccaro Kate McKinnon gwyneth paltrow